TRIPTOLIDE SECRETS

Furthermore, at different concentrations, triptolide was observed to induce the phosphorylation of p53 with the serine-15 residue in HepG2 cells. Activating the tumor suppressor gene p53 can induce the apoptosis of liver cancer cells 36.The pentacyclic triterpenoid celastrol has become recognized as An important bioactive metabolite of T. wilfordii